AIM:To evaluate the efficiency,security after implantation of iris-clawed anterior chamber intraocular lens(IOL) for the correction of high myopia. METHODS:Iris-clawed anterior chamber IOL were implanted for seven cases of patients with high myopia (13 eyes).After the following up for 12 months,visual acuity,intraocular pressure,corneal endothelial cells counting,the activity of the pupil,the position of IOL and complications were observed. RESULTS:The implantation was successfully performed in all of 13 eyes.After the following up for 7 days,the postoperative uncorrected visual acuity of 10 eyes(77%) was better than the preoperative best-corrected visual acuity.After the following up for 12 months,postoperative average uncorrected visual acuity(0.6±0.2) was better than the preoperative average best-corrected visual acuity (0.4±0.1),there was significant difference between preand post-operation(P<0.05).There was no significant difference between preoperative and postoperative corneal endothelial cells counting,intraocular pressure (all P>0.05).The position of IOL retained center well,the react to light of the patient’s pupils was normal,and complications such as cataract and corneal endothelial decompensation was not found,but two eyes occurred corticosteroid-induced glaucoma after 3-4 weeks,and the simple eye of one case occurred retinal detachment after six months. CONCLUSION:Iris-clawed anterior chamber IOL is an effective,safe operative technique for the correction of high myopia.Follow-up study is still required for the evaluation of long-term results.