·AIM:To explore the relation between retinal edema and Syndrome differentiation of TCM.·METHODS:Patients suffering CSC,CEC,MDM,AMD,RVO and DR had been chosen as study subjects.All cases were found retinal edema by FFA and OCT examination.Differentiate and sort general symptoms,zangfu location,pattern,the relation between retinal edema and Syndrome differentiation of TCM on the basis of complaint,tongue and pulse interpretation from patients.·RESULTS:Among 207 patients with retinal edema symptoms with frequency of occurrence above 20% were hypodynamia,anypnia,morbid forgetfulness,dizziness and loose stool.In the cases with found retinal edema pattern constituent:106 cases(51.2%)belong to spleen-QI deficiency;79 cases(38.2%)kidney-YIN deficiency;62 cases(30.0%)heart-blood deficiency;35 cases(16.9%)kidney-YANG deficiency;6 cases(2.9%)stagnation of Blood;12 cases(5.8%)Damp Heat and 20 cases(9.7%)no pattern.Deficiency was shown in 175 among 207 patients with retinal edema.·CONCLUSION:According to clinical manifestation and symptom,differentiation of neovascular had some regularity:spleen-QI deficiency pattern is the most,the second is kidney-YIN deficiency,the third is heart-blood deficiency.There were resemblance of appearance between internal medicine and retinal edema but pattern of syndrome had evident difference.Blood and YIN deficiency can result in retinal edema.Accoding to regional signs retinal edema shows the appearance of excess syndrome but its origin was deficiency of QI,Blood and YIN.By essence it was deficiency syndrome transforming into excess or simultaneous deficiency and excess.·