AIM:To investigate the clinical application of improved 23-gauge vitrectomy system in the treatment of vitreoretinopathy disease and evaluate its efficacy and safety.·METHODS:A retrospective study of 112 cases(112 eyes) who received improved 23-gauge vitrectomy from August 2009 to February 2010 was retrospectively studied. The diseases included rhegmatogenous retinal detachment(53 cases),tractional retinal detachment(59 cases).The main observation were the surgical effects and complications.The follow-up time was from 1 month to 12 months.·RESULTS:All cases were successfully completed without significant complications.The best-corrected visual acuity was improved in different degree.·CONCLUSION:Improved 23-gauge vitrectomy system with better curative effect,faster postoperative recovery and few complications is an effective and safe surgical technique for all vitreoretinopathy diseases.