Behcet’s disease (BD) is a chronic, recrudescent, systemic disease which involves multi-system and multi-organ. Uveitis caused by BD is a common type of uveitis inducing blindness in China. There is no radical cure for this kind of uveitis at present. IFN-α is a kind of cytokine which has multiple biological effects. It has a dual immunomodulatory activity, and has been applied to a variety of immune diseases in recent years. In-depth study of IFN-α will bring new hope for uveitis caused by BD treatment.