AIM:To study the basic characteristics of hospitalized neurological patients in the aspects of neuro-ophthalmology,for the further development of neuro-ophthalmology and better clinical treatment.METHODS:Clinical data of patients who had neuro-ophthalmology symptoms or signs in neurology department of our hospital from June 1,2009 to June 1,2010 were collected,retrospective method was used to study the disease constitution and the main clinical manifestations,then statistical analysis was used to get the conclusion.RESULTS:Totally 160 patients who had neuro-ophthalmology disorders were selected from 651 patients,accounting for 24.6% of the total number of neurology hospitalizations in the same period.The age range of patients was 13-86 years old,with a median of 54 years old,and was abnormal distribution.The main clinical manifestations:44 patients with diplopia,43 patients with movement disorders,42 patients with sustained vision loss and 38 patients with nystagmus.Constitution of the main diseases:cerebral infarction in 49,neuromyelitis optica(NMO) in 17,myasthenia gravis(MG) in 15,cerebral hemorrhage in 14,vertebrobasilar insufficiency in 12,cranial venous sinus thrombosis(CVST) in 5,multiple sclerosis(MS) in 5,inflammatory demyelinating disease in 5 and malignant brain tumor in 8,which accounted for 81.3%.Pathological nature:92 patients were cerebral circulation disorders,48 patients were non-infectious inflammation,8 patients were malignant tumor,4 patients were intracranial infection inflammation,3 patients were trauma,2 patients were poisoning,and 3 patients were unknown reasons.CONCLUSION:Of the total neurology inpatients,24.6% had neuro-ophthalmogy manifestations.The most common clinical manifestations are diplopia,eye movement disorder,sustained vision loss and nystagmus.Neuro-ophthalmogy disease spectrum of neurology includes cerebral infarction,NMO,MG,cerebral hemorrhage,vertebrobasilar insufficiency,CVST,MS,inflammatory demyelinating disease and malignant brain tumor.The main pathological disorders are cerebral circulation and non-infectious inflammation.