AIM:To discuss the experience on Laser treatment of central retinal vein occlusion(CRVO).METHODS:Forty-two 42 cases(42 eyes) of CRVO Laser treatment adopted different methods of photocoagulation treatment to explore its effects,according to the fundus fluorescein angiography(FFA) results.RESULTS:Visual acuity of 5 eyes(12%) of the 42 eyes improved 2 lines or more;28 eyes(67%) had no significant changes in vision;visual acuity of 9 eyes(21%) decreased by 2 lines or more;FFA examination showed tortuosity and expansion of retinal vein,retinal hemorrhage,edema and exudate subsided,treatment was effective in 37 eyes(88%).CONCLUSION:Laser treatment is effective for CRVO and is an important means to control the progression of the disease.