AIM:To investigate the feature of intraocular pressure(IOP) and ocular pulse amplitude(OPA) measured by dynamic contour tonometer(DCT) in the chronic angle-closure glaucoma(CACG),the primary angle-open glaucoma(PAOG),the normal tension glaucoma(NTG) and the healthy controls and to analyze the relation between the IOP and OPA.METHODS:Nineteen cases of chronic angle-closure glaucoma,18 cases of primary angle-open glaucoma,15 cases of normal tension glaucoma and 20 cases of healthy controls were taken into the measure.IOP,OPA were measured by DCT at the same time.One eye of each patient were taken into analysis randomly.All the patients accepted the blood pressure and the heart rates measure at the same time.The results were taken into analysis by SPSS 14.0.RESULTS:The mean IOP were 25.42±9.95mmHg,23.12±5.47mmHg,16.52±2.23mmHg and 16.31±2.67mmHg in CACG,PAOG,NTG and normal controls group.There were significant differences of IOP between the CACG group and NTG group(P<0.001).It was also observed between the PAOG group and NTG group(P=0.003).The mean OPA were 3.84±0.88mmHg,3.29±0.90mmHg,1.85±0.47mmHg and 2.47±0.80mmHg in CACG,PAOG,NTG and normal controls group.Significant difference of OPA was observed between the CACG group and the PAOG group(P=0.038).The OPA of the NTG group had significant difference with that of the CACG,the PAOG and the normal controls group(P<0.01,P<0.01,P=0.039).There were low correlations between the IOP and OPA in four groups.CONCLUSION:The statistical differences of OPA were among the CACG,the PAOG,the NTG and the healthy controls.There was low correlation between the IOP and OPA.