AIM:To evaluate the necessity,feasibility and effects of paracentesis of anterior chamber for acute angle-closure glaucoma with consistent high intraocular pressure(IOP).METHODS:The patients whose high IOP>40mmHg couldn’t be effectively reduced by drug treatment were randomly divided into 2 groups(group A and group B).Paracentesis of anterior chamber was performed on group A(treatment group) before operation,then performed tarbeculectomy after IOP returned to normal.And trabeculectomy was performed on group B(control group) under high IOP.The IOP,functional filter blebs,visual acuity,success rate of operation and complications of both groups were compared.RESULTS:No serious complications were found in group A.The IOP was decreased after paracentesis of anterior chamber.The eyes number and level of anterior chamber inflammation after operation in group A was slighter than that in group B(P<0.01).The rate of functional filter blebs formed,the success rate of operation,and the rate of visual recovery in group A were better than those in group B.The difference was significant(P<0.05,P<0.05,P<0.05,P<0.05).CONCLUSION:Paracentesis of anterior chamber as the auxiliary treatment of acute anger-closure glaucoma could shorten the time of reducing IOP,lessen visual function damage by high IOP,improve the success rate of operation,and reduce surgical complications.