AIM:To explore the relationships between height,weight and refraction and ocular biometries in children by cross-sectional study.METHODS:Study participants were recruited from the Guangzhou Twin Registry.The examination included visual acuity measurements,ocular motility evaluation,autorefraction under cycloplegia,and examination of the anterior segment,media,fundus.Axial length,anterior chamber depth,cornea curve radius was measured using partial coherence laser interferometry.Height and weight were measured with the participants standing without shoes.A multivariate linear regression model was used.RESULTS:Both axial length and anterior chamber depth grew with height and weight increase,but cornea curve radius kept steady.Adjusted by age and gender,spherical equivalent decreased-0.03D,axial length increased 0.03mm,anterior chamber depth deepened 0.002mm with 1cm height increase.But there was no association between weight and ocular biometries.CONCLUSION:There are associations between height and spherical equivalent,axial length,anterior chamber depth,and no association between weight and spherical equivalent,axid lenqth as well as anterior chamber depth.