AIM: To evaluate the visual outcomes and safety of combined pars plana vitrectomy(PPV),phaco-emulsification,and intraocular lens(IOL) implantation in the treatment of complex vitreoretinal diseases.METHODS: Retrospective consecutive interventional case series.137 eyes of 122 patients underwent combined PPV,phacoemulsification,and IOL implantation.Main outcome measures were visual acuity and complications.RESULTS: The mean follow-up was 12.8 months.The main vitreoretinal surgical indications were rhegmatogenous retinal detachment,tractional retinal detachment and proliferative diabetic retinopathy.In total,37 eyes(27.0%),55 eyes(40.1%) and 61 eyes(44.5%) gained two or more lines of vision compared with baseline at 1 month,6 months and 12 months follow-up.CONCLUSION: Combined PPV,phacoemulsification,and IOL implantation was safely and effectively used for cataracts and a variety of complex vitreoretinal diseases.