Posterior capsule opacification is a more common complication after cataract surgery.In recent years,with the development of molecular biology and cell biology technology,growth factor-type substances such as platelet-derived growth factor(PDGF) are found closely related with proliferation,migration,and differentiation of lens epithelial cell.The appropriate regulation of PDGF may be very important for the prevention of after cataract.This paper focuses on effect of PDGF on lens epithelial cells,effect of PDGF and its receptors on after-cataract formation in a brief review.