Abstract:AIM: To observe the early clinical efficacy of phacoemulsification combined with Bigbag, Sensar and PMMA intraocular lens(IOL) implantation in patients of high myopia complicated with cataract. METHODS: Totally 159 cases (202 eyes) patients received phacoemulsification combined with IOL implantation, in which implanted Bigbag, Sensar and PMMA IOL were 55, 71 and 76 eyes respectively. The best-corrected visual acuity (BCVA) 1 month after surgery, the difference of distance between posterior capsule with retina 1 month after surgery and preoperative, the postoperative complications of three groups were observed. RESULTS: In 1 month postoperation, the number and percentage of eyes with BCVA≥0.6 were 9 eyes (16.4%) in Bigbag group, 17 eyes (23.9%) in Sensar group and 11 eyes (14.5%) in PMMA group, the difference between any two groups was not statistically significant (P>0.05); the difference of distance between posterior capsule with retina 1 month after surgery and preoperative in Bigbag group was (1.52±0.11) mm, which was significantly smaller than Sensar group and PMMA group, the difference was statistically significant (P<0.05); the postoperative intraocular pressure(IOP) had no statistically difference among the three groups (P>0.05). No serious postoperative complications occurred in three groups. CONCLUSION: Bigbag IOL has no obvious superiority to increase visual acuity than other IOL, but because of its special design, it can play a stabilizing role of supporting the postoperative posterior capsule and weaken the vitreous rush forth so as to reduce the influence of phacoemulsification combined with IOL implantation for posterior segment of eyeball.