AIM:To discuss the role of amniotic membrane transplantation combined with mitomycin C (MMC) in the treatment of recurrent pterygium. METHODS:Totally 42 cases (47 eyes)of recurrent pterygium were treated with amniotic membrane transplantation combined with MMC, postoperative follow-up was 5-24 months. RESULTS:All graft survived, corneal epithelial defect completely healed, 2 patients relapsed during follow-up,the implant had no complications at corneal limbus. CONCLUSION:Amniotic membrane transplantation combined with MMC is a safe and effective method for the treatment of recurrent pterygium.