目的：探讨Sirius与Pentacam及超声测厚仪测量中央角膜厚度的一致性。 方法：对51例102眼正常人采用Pentacam和Sirius及超声角膜测厚仪三种仪器测量角膜厚度，记录并比较三种方法测量所得中央角膜厚度结果，同时运用Bland-Altman法绘制图表分析两两间一致性。 结果：A超中央角膜厚度平均值低于 Pentacam的平均值，Sirius中央角膜厚度的平均值最接近A超平均值。Sirius与Pentacam一致性的比较：其Bland-Altman图中3.92%的点在95%一致性界限以外。在一致性界限以内，Sirius与Pentacam中央角膜厚度差值的绝对值最大为19.5μm。Sirius与A超一致性的比较：其Bland-Altman图中2.94%的点在95%一致性界限以外。在一致性界限以内，Sirius与A超中央角膜厚度差值的绝对值最大为18.667μm。Pentacam与A超一致性的比较：其Bland-Altman图中582%点在95%一致性界限以外。在一致性界限以内，Pentacam与A超中央角膜厚度差值的绝对值最大为2533μm。 结论：Sirius系统与Pentacam系统具有良好的一致性，且Sirius系统比Pentacam系统更接近A超角膜测厚的结果。

AIM:To determine the agreement among Sirius pachymetric readings and the measurements made with Pentacam and ultrasonic pachymetry. METHODS:In this prospective study, 51 patients（102 eyes）with refractive surgery were enrolled and performed Pentacam and Sirius acquisitions followed by ultrasonic pachymetry. Pachymetric readings on central corneal thickness were recorded with Sirius, Pentacam and the ultrasonic system. Data were compared using t-tests, and the Pearson correlations and Bland-Altman analysis of all pairs were determined. RESULTS:Overall, ultrasonic measurements were significantly lower than all readings from the Sirius and the Pentacam，the Sirius was closest to the ultrasonic measurements values.In those Bland-Altman plots,3.92% of Sirius-Pentacam differences falled outside the 95% confidence limits for the mean difference.Within the limits of agreement,the maximum Sirius-Pentacam absolute difference was 19.5μm. 2.94% of Sirius-ultrasonic pachymetry differences falled outside the 95% confidence limits for the mean difference.Within the limits of agreement, the maximum Sirius-ultrasonic pachymetry absolute difference was 18.667μm. 5.82% of Pentacam-ultrasonic pachymetry differences falled outside the 95% confidence limits for the mean difference.Within the limits of agreement, the maximum Pentacam-ultrasonic pachymetry absolute difference was 25.33μm. CONCLUSION:Sirius system and Pentacam system have a good agreement , and the Sirius system is closer to ultrasound readings than Pentacam system over the results of corneal thickness.