AIM:To compare the differences in the central anterior chamber depth (CACD) and anterior chamber angle (ACA) measurements between emmetropia and high myopia eyes with Pentacam Scheimpflug. METHODS:In this prospective study, 82 healthy patients and 68 patients with myopia in the Affiliated Hospital of Mudanjiang Medical University were evaluated. Pentacam measurements were performed three times of one patient. A paired t-test was used to compare measurements of CACD and ACA width. The two groups were compared with SPSS 13.0. RESULTS:The differences in ACD and ACA values taken between the two groups were statistically significant (P<0.05). The ACD was deeper and the ACA was wider in patients with myopia. CONCLUSION:Patients with myopia have deeper ACD and wider ACA.