AIM:To analyse postoperative complications and prevention of retrograde intubation of lacrimal passage. METHODS:Complications statistics of 320 patients(352 eyes) were retrospectively analyzed.The causes and methods of prevention and treatment were investigated. RESULTS:Postoperative complications included lacrimal punctum split and laceration of canaliculus in 17 eyes (48%); puncta lacrimalis ,canaliculitis or dacryocystitis in 11 eyes(3.1%);granulation proliferation in 39 eyes (111%); extubation difficulties or stump residue in 19 eyes(5.4%)；false way in 3 eyes(0.9%)。 CONCLUSION:To avoid the complications, it is important to operate carefully and strictly control indications in retrograde intubation of lacrimal passage.