AIM:To discuss the security on patients with eld or concomitant systemic disease in scale cataract surgery. METHODS:The clinical data of 235 patients above 75 years or with systemic disease in “love and light” activity were retrospectively analysed. RESULTS:There were 213 cases (257 eyes) with systemic disease(90.6%). The ratios of circulation system disease, metabolic disease, and respiratory system disease were 65.1%, 13.6% and 11.1%, respectively. There were 25 cases (10.6%) deferring surgery because of the first preoperative evaluation of systemic disease and the surgery was done after effective treatment. The surgery off-disability and off-blindness rates were 95.4% and 84.2%, respectively. 12 cases with vision <0.1 had different degree of fundus disease. CONCLUSION:Strengthening preoperative comprehensive assessment, treating systemic disease fully, mastering operation indication strictly, monitoring in operation, operating legerity and 10-15 minutes surgery time were the effective measures to guarantee the security of patient with eld or concomitant systemic disease in scale cataract surgery.