AIM：To discuss the efficacy and safety of lifting flaps for laser in situ keratomileusis (LASIK) enhancement. METHODS：Totally 25 cases (36 eyes) of post-LASIK with residual refractive error were performed enhancement using lifting flaps, then ablated corneal stroma by excimer laser procedure. Postoperative follow-up survey included visual acuity, refractive error and complications for 1 year. RESULTS：The average uncorrected visual acuity improved from preoperative 0.39±0.16 to postoperative 092±0.17, 1.01±0.16, 1.03±0.16, 1.04±0.18 at 1 month, 3, 6, 12 months. The pre-operative mean spherical equivalent changed from -1.87±0.64D to 0.21±0.43D at post-enhancement 12 months. There was significant difference between them (P<0.01). CONCLUSION： Ｌifting flaps for LASIK enhancement is safe and effective to treat LASIK postoperative undercorrection and reftactive regression treatment.