AIM:To observe the clinical effect of the ReSTOR+3D multifocal intraocular lens (MIOL). METHODS:Fouty cases (80 eyes) with age-related cataract were divided into two groups with the same standard. 20 cases were bilaterally implanted with the Alcon ReSTOR+3D MIOL and another 20 cases with Alcon Nature blue-filter monofocal intraocular lens(SIOL) in different time. Both groups were performed clear corneal incision phacoemulsification combined with intraocular lens(IOL) implantation. Distance visual acuity and near visual acuity were observed at postoperatively l day. At postoperative 30 days, distance/near visual acuity, corrected distance/near visual acuity, best-corrected near visual acuity and contrast sensitivity(CS) were also observed. Visual quality, postoperative satisfactory and spectacle independence rate of each visual functional area were evaluated by questionaires. RESULTS:Allcases had good distance visual acuity postoperatively. The MIOL group was better than the SIOL group in uncorrected near and middle visual acuity. CS in the MIOL group was lower than that in the SIOL group, but there was no functional significance. In the MIOL group, 85% of the cases achieved total spectacle independence. CONCLUSION:The ReSTOR+3D multifocal IOL provides a satisfactory full range of vision, which is safe, effective and has high satisfactory.