AIM:To observe the etiological factor and clinical efficacy of comprehensive treatment for orbital cellulitis, and to improve its diagnostic method and provide its theoretical basis. METHODS:Totally 63 patients with orbital cellulitis form January 2009 to January 2012 in our hospital were analyzed. RESULTS:All patients were successfully healed within 2 weeks to 1 month without severe complication. CONCLUSION: The comprehensive treatment for orbital cellulitis with the advantages of definite effect is worth of promotion.