AIM: To discuss the clinical effect of using thefresh amniotic membrane and continuous ring lock shaped suture for the treatment of fungal corneal ulcer. METHODS:Twenty-one cases (21 eyes) with fungal corneal ulcer were treated by fresh amniotic membrane transplantation and continuous ring lock shaped suture, combined with lesion debridement and antifungal agents. RESULTS: Followed up for 3 months, among which 16 cases (16 eyes) were cured, 3 cases(3 eyes) improved, 2 cases(2 eyes) failed. CONCLUSION: Fresh amniotic membrane and continuous ring lock shaped suture for the treatment of fungal corneal ulcer is an effective therapy.