Abstract:AIM:To observe the protective effects of DuoVisc viscoelastic materials on low density corneal endothelium during cataract phacoemulsification and intraocular lens(IOL) implantation.METHODS:Twenty eyes of cataract with corneal endothelial cell density of 652.9-930.3/mm2 were observed. Before the surgery, the corneal endothelium density and central corneal thickness were recorded, then the patients underwent cataract phacoemulsification and IOL implantation in the capsular, the changes were observed during 7days postoperatively.RESULTS:In the early days after the surgery, 4 of these corneas were with mild edema, after medical treatment, they returned transparent. During postoperative 7days, the corneal endothelium cell densities after the surgery(735.6±92.6/mm2 )were not statistically less than before(798.2±113.1/mm2, P=0.145), the thickness of the central corneas were normal(0.53±0.02mm), which had no statistical significance compared with preoperatively(0.51±0.014mm, P=0.144).CONCLUSION:In the condition of mastering the technique of phacoemulsification, it is feasible to use DuoVisc viscoelastic materials in the surgery of cataract phacoemulsification and IOL implantation with low density corneal endothelium.