AIM:To discuss the methods and skills of secondary operation of intraocular lens(IOL) suture fixation after lensectomy-vitrectomy. METHODS:IOLs were implanted into 26 cases(26 eyes) after lensectomy-vitrectomy fixed in the ciliary grooves. The suture line was fixed on the sclera. The clinical curative effect and the complications were observed 3 to 24 months after operation. RESULTS:Seven cases had postoperative best-corrected visual acuity of＞0.5, 11 eyes were between 03 and 0.5, 8 eyes were between 0.1 and 0.3. Light IOL tilt was happened in 2 eyes, and 1 eye was corrected by operation. Intraocular hemorrhage was happened in 3 cases, hemorrhage was absorbed during 20 days. The intraocular hypertension was happened in 5 cases, 3 cases were controlled simply by corresponding treatment, 1 case was controlled by long-term drugs,1 case was controlled by implanting drain valve. Intraocular hypotension was happened in 4 cases, but all were controlled by corresponding treatment within 1 week.CONCLUSION:IOL implantation after lensectomy-vitrectomy was effective and responsible, the complications are fewer, which is an ideal method towards this kind of disease.