AIM:To analyze the clinical effect ofintegrated traditional Chinese and western medicine for the treatment of neovascular glaucoma(NVG).METHODS:Totally 251 cases(284 eyes)with NVG in glaucoma wards in eye center during January 2004 to January 2010 were collected, among which 150 cases(162 eyes) were treated with traditional Chinese medicine, 101 cases(122 eyes) were treated by single western medicine. Traditional Chinese medicine based on the principle of syndrome differentiation and treatment, taking traditional Chinese herbs according to the plus and minus of “Buyang Huanwu Decoction ”. Western medicine mainly treated with surgery. Panretinal photocoagulation(PRP) combined with vitreous injection of triamcinolone acetonide were performed in NVG stage 1. Compound trebeculectomy combined with amniotic membrane transplantation were performed in NVG stage 2. Ahmed valve implantation combined with anterior vitrectomy and vitreous injection of triamcinolone acetonide were performed in NVG stage 3A. While Ahmed valve implantation combined with vitrectomy and vitreous injection of triamcinolone acetonide were performed in NVG stage 3B and 3C. The intraocular pressure, visual acuity and iris neovascularization were observed 6 months after surgery.RESULTS:Compared with single western medicine, combined traditional Chinese medicine could improve the visual acuity of NVG in stage 1 and 2（Z_C=2.872,P<0.05；Z_C=8.017,P<0.05）, effectively control the intraocular pressure in stage 2 and 3（Z_C=4.557,P<0.05；Z_C=2.171,P<0.05）, promote iris neovascular regression in stage 2（Z_C=5.330,P<0.05）.CONCLUSION:The outcome of integrated traditional Chinese and western medicine is better than single western medicine for NVG.