Abstract:AIM:To evaluate the effect of dilated-free wide-angle laser scanning ophthalmoscope (OPTOS200) in screening the retinal peripheral lesions in patients with high myopia before refractive surgery. METHODS:Before refractive surgery, 72 cases 118 eyes with dioptor >-6.00D were examined with dilated-free wide-angle laser scanning ophthalmoscope and after pupil dilation three-mirror contact lens by two experienced physicians, and the peripheral retinopathy (with or without degeneration area, dry retinal tears, retinal detachment, etc.) were observed. Statistics of examination time of the two methods, number of eyes with lesions and total number of lesions were collected and comparatively analyzed.RESULTS:The average time of dilated-free wide-angle laser scanning ophthalmoscope examination was 4.16±1.22 minutes per eye, and that of post dilation three-mirror contact lens examination was 21.64±5.32 minutes, which was statistically different (P<0.01). Wide-angle laser scanning ophthalmoscope examination founded that 60 eyes (51%) were with peripheral retinal lesions, missed diagnosis in 4 eyes (founded by three-mirror contact lens), 6 eyes were with dry retinal tears, and total number of lesion was 87, 1 case with mild retinal detachment in the edge of tear. Three-mirror contact lens examination founded that 65 eyes (55%) were with peripheral retinal lesions, missed diagnosis in 1 eye(founded by wide-angle laser scanning ophthalmoscope), 8 eyes were with dry retinal tears, total number of lesion was 128, 3 cases with mild retinal detachment in the edge of tear. The number of eyes with lesions founded by the two methods had no significant difference (P>0.05), but the number of lesions per eye was statistically significant (P<0.05). The retinal degeneration areas undiscovered by wide-angle laser scanning ophthalmoscope were mainly located below, and covered by the upper eyelid in patients with small palpebral fissure. CONCLUSION:Wide-angle laser scanning ophthalmoscope (OPTOS200) has the same effect as three-mirror contact lens in peripheral fundus examination of patients with high myopia before refractive surgery. It is a convenient, non-invasive method, while its details and comprehensiveness are not as good as three-mirror contact lens, so we should recheck the lesions by three-mirror contact lens.