AIM: To observe the effect of vitrectomy combined with silicone oil tamponade for the treatment of endophthalmitis.

METHODS: Pars plana vitrectomy(PPV)combined with silicone oil tamponade was applied for the treatment of 21 cases with suppurative endophthalmitis. Anti-infection anti-inflammatory therapy was given subconjunctivally by vein, and eye drops postoperatively.

RESULTS: Followed up for 3-12 months after PPV, 21 cases of bacterial infection was controlled, the postoperative visual acuity had significantly increased compared with preoperation.

CONCLUSION: PPV combined with silicone oil tamponade can control inflammation, stabilize retinal function. For the treatment of some suppurative endophthalmitis patient with retinal circumstance or inflammation, the curative effect is accurate and reliable, the method is worthy of promotion.