AIM:To observe the effect of 1g/L pranoprofen eye drops in the treatment of dry eye.

METHODS: A total of 100 dry eyes patients, from the outpatient department in our hospital between January and December of 2011, were randomly divided into two groups: group A was treated by 1g/L pranoprofen drops combined with 1g/L sodium hyaluronate eye drops, 1 drop each time, 4 times/d for each eye; group B was treated by 1g/L sodium hyaluronate eye drops alone, 1 drop each time, 4 times/d, for each eye, All patients met the inclusion criteria before treatment and were observed before and after 14 days of treatment with questionnaire scores, Schirmer Ⅰ trial, corneal fluorescein staining scores. The results of the two groups were compared for statistical analysis.

RESULTS: The effect of 1g/L pranoprofen eye drops combined 1g/L of sodium hyaluronate eye drops was significantly better than that of 1g/L of sodium hyaluronate eye drops in the treatment of dry eye patients. There was significant difference between two groups.

CONCLUSION: 1g/L pranoprofen is effective for dry eye to relieve symptoms and improve corneal situation.