AIM: To explore the safety and effectiveness of double frequency 532 laser peripheral iridoplasty(LPI)in treatment of acute attack of primary angle-closure glaucoma(PACG)which isn't suitable for drugs.

METHODS: Thirteen consecutive patients with acute PACG were recruited into the study. Each patient received oxybuprocaine(4g/L), and double frequency 532 LPI immediately. The intraocular pressures(IOP)of 15 minutes, 30 minutes and 60 minutes after double frequency 532 LPI were documented.

RESULTS: The mean IOP of this group of patients was reduced from 60.6 ±8.8mmHg(1kPa=7.5mmHg), before double frequency 532 LPI to 37.4 ±7.3mmHg in 15 minutes, 26.2±6.6mmHg in 30 minutes, and 17.1±5.3mmHg in 60 minutes after LPI. The cornea edema patients cleared up, no serious complications.

CONCLUSION: Double frequency 532 LPI in the treatment of PACG is safe, effective, and can be used for treatment of first choice.