AIM: To observe the clinical effect of compound anisodine injection for the treatment of anterior ischemic optic neuropathy(ION).

METHODS: From December 2011 to June 2012, 82 patients with anterior ION were selected as objects in our hospital, they were all ill in single eye. They were randomly divided into observation group and control group. Observation group(compound anisodine injection group, n=42)and control group(salvia hormone injection group, n=40). We observed the curative effects.

RESULTS: In observation group, the total effective rate was 88.1% after 2 courses of treatment, it was significantly higher than the control group, after χ² test, P<0.05. The complication rate was 2.4%, the differences were not apparent when compared with the control group, after the χ² test, P>0.05.

CONCLUSION: The clinical effect of compound anisodine injection for the treatment of anterior ION was obvious, it does not increase the incidence of adverse reactions when combined with traditional methods, it has the characteristics of safety, simple, and easy to practice.