AIM: To investigate the diagnosis and treatment of neonatal conjunctivitis.

METHODS: Totally 100 cases of neonatal conjunctivitis patients admitted to our hospital from January 2008 to January 2010 by order of admission were randomly divided into observation group and control group, with 50 cases in each group, the observation group was given ofloxacin drops eye drops while the control group was given penicillin eye drops, the efficacy, eye secretions disappeared time, conjunctival hyperemia disappeared time, transparent cornea time were compared between the two groups.

RESULTS: After the treatment, the effective rate of 98.0% in the observation group which was significantly higher than the 88.0% of control group(χ²= 3.84, P<0.05); the eye secretions disappeared time, conjunctival hyperemia disappeared time, transparent cornea time in the observation group were significantly lower than that in the control group(P<0.01).

CONCLUSION: The ofloxacin had excellent therapeutic efficacy for treating with neonatal conjunctivitis, and it can effectively improve the cure rate and shorten children's eye secretions, conjunctival hyperemia disappear and cornea transparent time.