AIM: To observe the clinical effect and visual function of laser in treatment of central serous chorioretinopathy(CSC).

METHODS: Totally 60 cases clinically diagnosed with CSC were randomly divided into laser treatment group and drug treatment group, 30 cases in each group.Visual acuity and changes of mfERG in two groups were observed, and patients were followed up for 6 months.

RESULTS: The treatment of vision effective rate in laser treatment group was 92.35% and after one month with no patient recrudesced. The treatment of vision effective rate in drug treatment group was 49.58% and the recurrence rate was 13.33%. mfERG showed the response densities of ring 2, ring 3, ring 4 and ring 5 areas in laser treatment group were significantly increased while the latencies of ring 4 of N1 wave and the latencies of ring 3, ring 4 and ring 5 of P1 wave were significantly different with drug treatment group(P<0.05).

CONCLUSION:Early treatment of CSC with laser can significantly improve visual function and recovery rate, prevent disease progression, and decrease the recurrence rate, especially at early stage of the disease.