AIM: To confirm the hypothesis that "Blink is the power of discharge basal tear secretion, we make many clinical observations.

METHODS: Clinical observation of 4 216 people of the following items:(1)Epiphora symptoms in the 60 lacrimal duct obstruction patients during sleeping period.(2)26 symptoms of epiphora in the 30 wakefulness closed eyes.(3)300 new birth baby's blink and epiphora.(4)observed more than 300 people's blink.(5)observed in vivo 360 eyes discharged tear effect after the lacrimal retrograde(6)observed the exposure keratitis patients' basal tear secretion.

RESULTS:(1)All causes of the different types of lacrimal duct obstruction patients stop epiphora symptoms.(2)Patients in coma and with the blepharophimosis dysraphism exposure keratitis, reflex arc did not appear.(3)26 cases with lacrimal duct obstruction meditatively without epiphora symptoms during their eyelid closing and 4 cases significantly reduced.(4)In neonates: the first crying tears was only 10%, most newborns crying tears happened 7 to 20 days after birth, all of the neonates had blink action after birth.(5)Observation in vivo the fluid levels in the lacrimal retrograde catheterization drainage tube, the level was down when eye opened, and the water liquid-level rise when eyes closed, the rate was about 2.0mm.(6)Random observed 300 normal people blink rate, rhythm and blink duration and self-restraint under the gaze of the slowest, the horizontal gaze center, and three upward gazes fastest. Downward gaze eye position to suppress the longest duration of the blink.

CONCLUSION: The clinical observations confirmed the hypothesis that “Blink is the power of discharge basal tear secretion”. But it needs further clinical and laboratory research to further verification.