AIM: To observe the function of optic nerve and the thickness peripapillary retinal nerve fiber layer(RNFL)in elder age amblyopia.

METHODS: Pattern visual evoked potential(P-VEP)and optical coherence tomography(OCT)were compared between >12 years elder amblyopia group(30 cases, 30 eyes)and normal group(15 cases, 30 eyes).

RESULTS: The amplitudes of the P100 wave(P-VEP)inamblyopia group were lower and latencies were longer compared with normal group(P<0.05), and the average RNFL thickness of optic disc using OCT from amblyopia group were thinner than those of the normal group(P<0.05).

CONCLUSION: There are significant abnormal of the conduction from the optic nerve and the retinal structure in elder amblyopia.