[关键词]
[摘要]
目的：观察大龄弱视患者视神经功能和视网膜神经纤维的变化特征。
方法：选择大于12岁的大龄弱视患者30例30眼，并选取年龄相当的正常人15例30眼作为对照，利用图形视觉诱发电位(pattern visual evoked potential， P-VEP)、光学相干断层扫描(optical coherence tomography， OCT)等技术，观察大龄弱视视神经功能和神经纤维形态学的变化特征。
结果：大龄弱视患者P-VEP的P100波振幅均较正常组降低、潜伏期延迟(P<0.05)； OCT显示大龄弱视组视盘周围神经纤维较正常组明显降低(P<0.05)。
结论：大龄弱视患者视神经传导功能和视网膜神经结构均存在异常。
[Key word]
[Abstract]
AIM: To observe the function of optic nerve and the thickness peripapillary retinal nerve fiber layer(RNFL)in elder age amblyopia.
METHODS: Pattern visual evoked potential(P-VEP)and optical coherence tomography(OCT)were compared between >12 years elder amblyopia group(30 cases, 30 eyes)and normal group(15 cases, 30 eyes).
RESULTS: The amplitudes of the P100 wave(P-VEP)inamblyopia group were lower and latencies were longer compared with normal group(P<0.05), and the average RNFL thickness of optic disc using OCT from amblyopia group were thinner than those of the normal group(P<0.05).
CONCLUSION: There are significant abnormal of the conduction from the optic nerve and the retinal structure in elder amblyopia.
[中图分类号]
[基金项目]
深圳市科技局基金资助课题(No.200702086)
