AIM: To analyze the clinical effect of perioperative intervention in proliferative diabetic retinopathy(PDR)patients.

METHODS: Totally 52 cases of eye diabetic retinopathy with medical records and follow-up materials were retrospectively analyzed from May 2009 to December 2011, male 15 cases, female 25 cases, age 31 - 78 years old, all patients underwent preoperative visual acuity, intraocular pressure, slit lamp microscope, slit lamp microscope eye fundus examination, B ultrasonic, corneal endothelial mirror etc. After 1 week, 2 weeks, 1 month, 2, 3, 6 months follow-up, the patients were observed the vision, intraocular pressure, artificial crystal, fundus, perioperative observation of patients with blood glucose, blood pressure, systemic, adverse events, and so on. Implementation of all patients perioperative interventions. According to the patients with diabetes related systemic complications diagnosis rating, each complication was recorded as 1 point, no complication 0. Operation method for vitrectomy + full retinal photocoagulation, merger macular edema and macular front wall line macular inside boundary film stripping, who do the same period with cataract phacoemulsification, stage I or implant implantation of artificial crystal, according to the intraoperative situation intraocular filling long-term gas/oil/song amine Ned; During the operation, the conventional for ecg monitoring, appear obvious blood pressure fluctuation in anesthesia physician care descending controlled decompression.

RESULTS: Forty cases of 52 eyes of diabetic retinopathy in patients with type I 5 cases, eyes surgery of 12 patients(30%), each eye around 14 cases(35%), PDR stage IV 15 eyes(28.8%), V stage 16 eyes(30.7%), VI period 21 eyes(40.3%). Preoperative sight is lower than 0.02 and eyes(73.1%), 0.02 - 0.1 7(13.5%)eye, 0.1 - 0.3 5 eyes(9.6%), more than 0.3 2 eyes(3.8%). In the follow-up of sight is lower than 0.02 17 eyes(32.7%), 0.02 - 0.1 9 eyes(32.7%), 0.1 - 0.3 14 eyes(32.7%), 0.3 above 12 eyes(23.1%). One surgery cured 47 eyes(90.4%), reoperation five eyes(9.6%), early postoperative mild vitreous hemorrhage again five eyes(9.6%), late again vitreous hemorrhage along with neovascular glaucoma 1 eyes(1.9%), infectious endophthalmitis 1 eye(1.9%). The material in our hospital medicine diagnosed with complications of patients for 17 cases(42.5%), no complications of 23 cases(57.5%), the score of 0 points 23 cases, 1 points, nine cases(22.5%), 2 points, four(10%), 3 points in 3 patients(7.5%), 4 points 1 cases(2.5%). During the operation, the implementation of controlled decompression five eyes(9.6%). All patients perioperative blood glucose, blood pressure and body were stable, no adverse events.

CONCLUSION: The perioperative intervention can significantly reduce the diabetes patients with systemic complications and adverse events, but the cost of patient care increased; Stable blood sugar, blood pressure and appropriate drug therapy can reduce the incidence of early vitreous hemorrhage again. Vitreous surgery or joint operation treatment is an effective means of PDR, surgical indications and timely grasp the surgical treatment of the patients with visual function is the key to save the residual of visual function.