AIM: To investigate the influence of protein free calf blood extract eye gel on dry eye after pterygium surgery.

METHODS: Thirty six patients(40 eyes)with primary nasal pterygium were enrolled in this study, which were divided into study group and control group randomly, with 20 eyes in each group. All patients received pterygium excision and limbal stem cell autograft surgery and tobramicin dexamethasone eye drops after surgery. Patients of the study group received protein free calf blood extract eye gel while those of the control group received 0.1% sodium hyaluronate eye drops furthermore. Ocular surface disease index(OSDI)questionnaire, tear film break-up time(BUT)and Schirmer's Ⅰ test Ⅰ(SⅠt)were carried before and 3 months after surgery to evaluate the dry eye degree of the patients.

RESULTS: There was no statistical difference between the age, gender and size of the pterygium of the study and control groups preoperatively. There was no statistical difference between the OSDI(2.33±1.02 vs 2.32±0.93), BUT(8.80±2.48 vs 8.35±2.28)seconds and SⅠt(4.30±2.30 vs 4.40±2.44)of the two groups preoperatively. There was statistical difference between the OSDI(1.45±0.47 vs 1.81±0.60), BUT(11.20±2.07 vs 9.50±2.40)seconds and SⅠt(8.35±3.13 vs 6.35±2.18)of the two groups 3 months postoperatively, which was also different from that of the preoperative data correspondingly.

CONCLUSION: Protein free calf blood extract eye gel could reduce the dry eye after pterygium surgery.