AIM: To investigate the causes of descemet membrane detachment, and put forward the treatment and prevention methods.

METHODS: A retrospective analysis of 30 cases(30 eyes)with decement membrane detachment was investigated. Gas tamponade in anterior chamber was performed, after 6 months of follow-up, the corneal transparency and visual acuity were observed.

RESULTS: Cataract and glaucoma were common causes of decement membrane and detachment, 25 of the 30 cases had vision improved obviously after gas infusion in anterior chamber, 27 patients with recovery of corneal transparency.

CONCLUSION: The decement membrane detachment has great effect on cornea, it should be promptly dealt with, otherwise it can easily cause corneal persistent injury.