AIM: To study the efficacy of a single intravitreal injection of perfluoropropane(C₃F₈)in releasing vitreomacular traction.

METHODS: Twelve eyes of 12 consecutive patients with vitreomacular traction received a single intravitreal injection of 0.3mL 100%(C₃F₈)were retrospectively analyzed. The best corrected vision acuity and the neural epithelium thickness of central macular were observed.

RESULTS: One month following treatment, vitreomacular traction was released in 5 eyes(42%), mean final visual acuity(VA)improved 0.04 and mean central foveal thickness decreased by 69μm. The vision acuity before and after treatment were 0.20±0.07, 0.25±0.04 respectively.

CONCLUSION: Intravitreal C₃F₈ injection could offer a minimally invasive alternative to pars plana vitrectomy in patients with vitreomacular traction.