AIM: To analyze the prognosis and influencing factors of retinopathy of prematurity(ROP).

METHODS: The prognosis of 145 ROP cases treated in our hospital from September 2011 to September 2012 was recorded(110 males, 35 females). Gestational weeks, birth weight, time of oxygen, oxygen \〖continuous positive airway pressure(CPAP)or mechanical ventilation\〗, pulmonary surfactant, septicemia were statistically analyzed between surgical group and non-surgical group.

RESULTS: A total of 145 cases of retinopathy of premature were all in stage 1 to 3, no cases in 4 to 5 stage. Thirty-six cases(24.8%)had undergone the laser and/orcryocoagulation. ROP regressed completely or were stable before prethreshold lesions without surgery in 109 cases(75.2%). Using the Chi-square test, multivariate logistic regression analysis, it showed that gestational age, time of oxygen, CPAP or mechanical ventilation and septicemia were associated with ROP outcome, with the statistically significant difference. Gestational age, oxygen, septicemia were progression factors of ROP, which was significant difference between groups.

CONCLUSION: Most of ROP degenerated or were stable without surgery.Gestational age, mechanical ventilation or CPAP, oxygen for a long time, septicemia could aggravate ROP and increase the probability of surgery.