AIM: To evaluate the efficacy and clinical significance ofglycosylated hemoglobin(HbAlc)determination on diabetic cataract surgery.

METHODS: Totally 105 patients with diabetes(120 monocular)undergone phacoemulsification in our hospital from March 2012 to March 2013 were enrolled into the observation group(glycosylated hemoglobin determination group, HbA1c <6.5%). One hundred and eleven patients received diabetic cataract phacoemulsification surgery(126 monocular)in our hospital from January 2011 to March 2012 were reviewed as control group(blood glucose group, blood glucose <6.4mmL/L). Both of the groups were performed phacoemulsification with IOL intraocular lens implantation. Postoperative anterior segment inflammatory response(TASS), visual acuity and intensity of use of antibiotics(DDD)of the two groups' were compared during the following-up.

RESULTS:Glycated hemoglobin determination group: the mean visual acuity recovery was 0.72, the incidence of TASS was 83.3%, and DDD was 45.5. Blood glucose group: those were 0.498, 93.7%, and 88.6. The difference of incidence, degree and occurrence time of TASS(SAS 15.0 software analysis)and the degree of visual recovery between the two groups were statistically significant(P<0.05). The values of DDD were significantly different(P<0.01).

CONCLUSION:Glycosylated hemoglobin determination is the gold standard to measure blood sugar preoperation and has important significance for choosing the right time for diabetic cataract surgery. TASS was significantly reduced in the patients with preoperative standard glycosylated hemoglobin, the visual acuity of them improved significantly, and DDD values were significantly lower.