直角边缘囊袋张力环预防兔后囊膜混浊的实验研究
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Preventive effect of sharp-edged capsule tension ring on posterior capsule opacification
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    摘要:

    目的:探讨直角边缘囊袋张力环(capsule tension ring,CTR)预防兔后囊膜混浊(posterior capsule opacification,PCO)的作用。

    方法:新西兰兔20只随机分为两组,进行超声乳化晶状体摘除术后,实验组植入CTR 和Crane OV-55C 人工晶状体(intraocular lens,IOL),对照组只植入Crane OV-55C IOL。观察术后并发症和PCO情况。术后3mo行光镜和透射电镜检查,观察晶状体后囊膜的形态学变化。

    结果:术后3mo实验组和对照组都发生了明显的PCO(P>0.05),各组Soemmering环形成程度无统计学差异(P>0.05)。病理学检查发现,两组兔赤道部晶状体上皮细胞增生形成了巨大的Soemmering环,大量晶状体上皮细胞移行至后囊膜。

    结论:直角边缘CTR未能预防兔PCO的发生,有必要对其进一步改进。

    Abstract:

    AIM: To evaluate the effect of sharp-edged capsule tension ring(CTR)on posterior capsule opacification(PCO).

    METHODS: Twenty eyes of New Zealand white rabbits were randomly divided into two groups. After phacoemulsification, the experimental group was implanted with CTR and Crane OV-55C intraocular lens(IOL), and the control group was implanted with Crane OV-55C IOL only. Complications and PCO were observed by slit lamp microscope. Three months after surgery, light microscope and transmission electron microscope examinations were performed.

    RESULTS: There was no statistically significant difference between the experimental group and the control group about PCO and Soemmering's ring formation(P>0.05). Pathological evaluations revealed lens epithelial cells(LECs)accumulated at the equatorial capsule forming a large Soemmering's ring and abundant LECs were migrated onto the posterior capsule forming a thick layer in both experimental group and the control group.

    CONCLUSION: Sharp-edged CTR fail to retard PCO formation and development in rabbits and it is nessessary to improve it.

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石海红,吴坚,杨铃.直角边缘囊袋张力环预防兔后囊膜混浊的实验研究.国际眼科杂志, 2013,13(9):1762-1764.

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  • 收稿日期:2013-04-16
  • 最后修改日期:2013-08-18
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  • 在线发布日期: 2013-08-26
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