三种抗青光眼手术对青光眼患者术后生活质量的影响
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Effects of traditional trabeculectomy, mitomycin C trabeculectomy and sclera pool trabeculectomy on post-surgical life quality in glaucoma patients
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    摘要:

    目的:探讨并比较传统小梁切除术、丝裂霉素C(MMC)小梁切除术与巩膜池小梁切除术对青光眼患者术后生活质量的影响。

    方法:将60例60眼接受手术治疗的青光眼患者随机平均分为A组、B组与C组。A组20例20眼患者接受传统小梁切除术治疗; B组20例20眼患者接受MMC小梁切除术治疗; C组20例20眼患者则接受巩膜池小梁切除术治疗。在术后1a对患者进行随访,观察并比较各组患者中文版低视力者生存质量量表(CLVQOL)及自我生活质量量表各分项及总分。

    结果:与A组相比,B组及C组CLVQOL各分项及总分均显著升高(P<0.05),C组在总分及两项分项得分(“远视力、移动及光感”以及“阅读及精细工作”)改善比B组更为显著(P<0.05); 与A组相比,B组及C组自我评价量表总平均分及各分项得分均显著升高(P<0.05),其中C组在总平均分及两项分项得分(“视力自我评分”及“主观亮度评分”)改善更为显著(P<0.05)。

    结论:巩膜池小梁切除术对青光眼患者术后生活质量改善较明显,显著优于传统小梁切除术及MMC小梁切除术。

    Abstract:

    AIM: To explore and compare the effects of trabeculectomy, mitomycin C(MMC)trabeculectomy and sclera pool trabeculectomy on life quality of patients with glaucoma.

    METHODS: Totally, 60 patients(60 eyes)with glaucoma were divided into group A, B and C equally and randomly. Twenty patients(20 eyes)in group A received treatment of traditional trabeculectomy; Twenty patients(20 eyes)in group B received MMC trabeculectomy; while twenty patients(20 eyes)in group C received sclera pool trabeculectomy. One-year follow study was proposed, Chinese version low vision quality of life questionnaire(CLVQOL)and self- assessment score were used to evaluate effects of surgeries on life quality of patients.

    RESULTS: Compared with group A, scoring of CLVQOL increased significantly in group B and C, and more significantly in group C(distant vision, movement, sensitization and fine work)when compared with group B(P<0.05). Compared with group A, scoring of self assessment increased significantly in group B and C, more significantly in group C(vision self scoring and subjective brightness scoring)when compared with group B(P<0.05).

    CONCLUSION: The improvement effect of sclera pool trabeculectomy on life quality of patient with glaucoma is better than traditional and MMC trabeculectomy.

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周卓琳,马千丽,杨新光,等.三种抗青光眼手术对青光眼患者术后生活质量的影响.国际眼科杂志, 2013,13(9):1822-1825.

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  • 收稿日期:2013-06-30
  • 最后修改日期:2013-08-09
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  • 在线发布日期: 2013-08-26
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