Abstract:AIM: To evaluate the clinical efficacy of lamellar keratoplasty combined with anterior chamber injections in the treatment of fungal corneal ulcer.
METHODS:Patients who are diagnosed with fungal corneal ulcer and treated with layer corneal transplantation were in control group. Those with fungal corneal ulcer that treated with lamellar keratoplasty in experimental group, as well as they were injected with 0.1mL fluconazole(0.05mL 2g/L fluconazole +0.05mL normal saline)into the anterior chamber for three times during operation, at the 3rd day and 10th day after operations.
RESULTS: The recurrence rate was 11% in control group, while no recurrence for experimental group in a 3- to 6-month follow-up observation.
CONCLUSION: The combination of anterior chamber injection into lamellar keratoplasty is an efficient approach to cure fungal corneal ulcer, and shows low recurrence rate.
