影响LASEK乙醇浸润法制备角膜上皮瓣时间的相关因素
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Analysis of factors influencing preparation of corneal flap time in LASEK
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    摘要:

    目的:探讨影响LASEK角膜上皮瓣制作时间的相关因素。

    方法:回顾性分析选取2009-08/2012-08在我院行LASEK治疗的近视患者320例640眼,将患者按年龄分组,18~23岁、24~29岁、30~35岁、大于35岁4组(A,B,C,D),每组按是否配戴隐形眼镜超过3mo,分为2个亚组(I,II),统计每组的平均制瓣时间。

    结果:大部分患者于术后2~4h后有异物感、疼痛等眼部刺激症状。术后7d左右角膜上皮基本愈合,20d左右视力基本恢复到最佳。术后6mo平均裸眼视力1.23±0.15。制瓣时间11~30(平均18±3.5)s,随着年龄的增加,制瓣时间明显延长,配戴隐形眼镜的时间大于3mo的患者,制瓣时间也明显延长,同年龄段2个亚组(Ⅰ,Ⅱ)作统计学处理,差异有显著性(P<0.05)。同年龄段男、女患者制瓣时间差异不明显(P>0.05)。

    结论:随着年龄的增加,制瓣时间明显延长。长期配戴角膜接触镜是影响上皮瓣制作成功的重要因素,配戴隐形眼镜的时间大于3mo的患者,制瓣时间也明显延长。

    Abstract:

    AIM:To explore the factors affecting on the making time of LASEK corneal flap.

    METHODS:A retrospective analysis from August 2009 to August 2012 in our hospital in 320 cases treated by LASEK in myopic patients(640 eyes), the patients were grouped according to age, 18-23 years, 24-29 years, 30- 35 years, and greater than 35 year were divided into 4 groups(A, B, C, D), each group according to whether wearing contact lenses for more than 3 months, divided into 2 subgroups(I, II), the average flap preparation time statistics for each group.

    RESULTS: Most of the patients in postoperative 2-4h after a foreign body sensation, presented ocular pain. Corneal epithelium was basically healed after about 7days. Visual acuity recovered to the best after 20d. After 6 months, the average visual acuity was 1.23±0.15. Flap preparation time 11-30s, average 18±3.5s. With the increase of age, flap preparation time was significantly prolonged. For those wearing contact lens over 3 months, flap preparation time was significantly longer. There was significant difference(P<0.05)after analyzing the same age as 2 subgroups(I, II). Flap preparation time in male and female patients with the same age had no significantly difference(P>0.05).

    CONCLUSION: With the increase of age, flap preparation time is significantly prolonged. Long-term wear contact lens is the important factor in the success of production. For those wearing contact lens over 3 months, flap preparation time was significantly longer.

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魏芬,艾明,许鸣,等.影响LASEK乙醇浸润法制备角膜上皮瓣时间的相关因素.国际眼科杂志, 2013,13(10):2157-2159.

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  • 收稿日期:2013-07-24
  • 最后修改日期:2013-09-12
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  • 在线发布日期: 2013-09-23
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