AIM: To investigate the changes of macular retinal thickness after laser in situ keratomileusis(LASIK)in myopia.

METHODS: Totally 138 eyes of 69 patients who underwent LASIK were recruited randomly. The average macular retinal thickness, and volume of nine zones which were the areas of 0.5mm diameter around the macular fovea, the superior, nasal lateral, anterior and bitamporal lateral of 1.5mm and 3mm diameter around from it, were measured pre-operatively and at 1 day, 1 week, 1 month, 3 and 6 months postoperatively by the use of optical coherence tomography(OCT).

RESULTS:Compared with pre-operation, the retinal thickness and volume of 1.5mm diameter around the macular fovea areas(A1, A2, A3, A4)was lower at 1 day, 1 week, and was no obvious difference on 1 month, 3 and 6 months after operation; the areas of 0.5mm(A0)and 3mm(A5, A6, A7, A8)diameter around the macular fovea was no obvious difference at 1 day, 1 month, 3 and 6 months.

CONCIUSION: The changes on part of macular retinal thickness are mild reversible in LASIK surgery.