AIM: To observe the change of tear meniscus measured by OCT to determine the effects of Augentropfen Stulln Mono eye-drops on the tear dynamics of dry eyes after and to evaluate its efficacy and persistence in treating dry eye.

METHODS: A total of 25 patients, average age being 28.60±3.77, after excimer laser surgery(more than 6 months)were selected in the study. All patients had complications such as dry and sore eye and the tear break-up times(BUT)were less than 5s. The right eyes in the experimental group were given Augentropfen Stulln Mono eye-drop and the left eyes in the control group were given 0.9% normal saline. The heights and cross-sectional areas of the upper and lower tear menisci were measured by OCT before drop instillation and at 10min, 20min and 30min after drop instillation. Differences in each eye at different times were analyzed by one-way variance and compared by sample T test.

RESULTS: The lower tear meniscus cross-sectional area(t=2.835, P=0.009)at 20min after drop instillation, and the upper tear meniscus height(UTMH)(t=2.368, P=0.026), upper tear meniscus cross-sectional area(UTMA)(t=4.293, P=0.000), lower tear meniscus height(LTMH)(t=3.060, P=0.005)and lower tear meniscus cross-sectional area(LTMA)(t=2.644, P=0.014)at 30min after drop instillation in the experimental group were significantly larger than that in the control group with no statistical differences. There were no statistically significant differences in upper and lower tear meniscus heights and cross-sectional areas between two groups before and after taking drugs(P>0.05), however, there was a trend of increase after treatment in the experimental group.

CONCLUSION:Augentropfen Stulln Mono eye-drops can increase the volumes of upper and lower tear meniscus in patients with dry eyes after operation to some degree, and can maintain effects in a relatively long time period.