Meibomian gland dysfunction(MGD)is a chronic disffuse abnormality of the meibomian glands, commonly characterized by terminnal duct obstruction and/or qualitative/quatitative changes in the glandular secretion. The evaporative dry eye disease is mainly caused by MGD. In recent years, the morbidity of the evaporative dry eye disease which caused by MGD is raising, researchers both at home and abroad pay more attention on that. There is no uniform standard on MGD' treatment internationally. It is mainly centered on removing the cause and applicating the local and systemic therapy, including physicotherapeutics, drug therapy, artificial tears replacement therapy, nutrition support therapy, hormonotherapy, Chinese medicine treatment etc. The literature review is mainly talking about the treatment of dry eye which caused by MGD on both at home and abroad.