糖尿病性白内障超声乳化摘除术前后角膜内皮细胞变化
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辽宁省自然科学基金(No.201102130)


Clinical observation of changes of corneal endothelial cells before and after the cataract ultrasonic emulsification for diabetics
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Natural Science Foundation of Liaoning Province, China(No.201102130)

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    摘要:

    目的:观察白内障超声乳化联合人工晶状体植入术对糖尿病患者角膜内皮细胞的影响。

    方法:糖尿病组:白内障合并糖尿病患者39例52眼,对照组:白内障非糖尿病患者31例33眼,应用角膜内皮检测仪于术前及术后1d; 1wk; 1mo测量角膜内皮细胞密度、六角形细胞比率,分析结果。

    结果:糖尿病组和对照组术后1d; 1wk; 1mo角膜内皮细胞密度、六角形细胞比率均比术前显著降低(P<0.05),糖尿病和对照组术前角膜内皮细胞密度、六角形细胞比率均无显著性差异(P>0.05),但术后1d糖尿病组患者角膜内皮细胞丢失明显高于对照组(P<0.05)。糖尿病组按年龄分三组,分别为50~60岁、61~70岁、71~80岁,术后角膜内皮细胞损失量无统计学意义(P>0.05)。

    结论:白内障超声乳化术对角膜内皮细胞有一定的损伤,糖尿病患者比非糖尿病患者角膜内皮更易受损,糖尿病患者角膜内皮的损伤与年龄无关。

    Abstract:

    AIM: To observe the influence on the corneal endothelial cells after the cataract ultrasonic emulsification combined with intraocular lens implantation in patients with diabetes.

    METHODS:Diabetic group: 52 eyes from 39 cataract patients with diabetes. Control group: 33 eyes from 31 cataract patients without diabetes. The density and the percentage of hexagonal cells of the corneal endothelium were measured by corneal endothelial detector preoperatively and 1d, 1wk, 1mo after the surgery. The results were analyzed.

    RESULTS:The density, ratio of hexagonal cells of the corneal endothelial cells were significantly lower than before(P<0.05)postoperative in two groups, there was no significant difference the two groups before treatment, but the corneal endothelium loss in diabetes group was more than those in control group at 1d after treatment(P<0.05). Diabetes group is divided into three groups according to age 50-60 years old, 61-70 years old,71-80 years old, the postoperative corneal endothelial cell loss had no statistical significance(P<0.05).

    CONCLUSION: The cataract ultrasonic emulsification damages the corneal endothelium, and it is more easy to be damaged in diabetics. Diabetic corneal endothelial injury has nothing to do with age.

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苏畅,刘丹.糖尿病性白内障超声乳化摘除术前后角膜内皮细胞变化.国际眼科杂志, 2014,14(2):273-275.

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  • 收稿日期:2013-10-23
  • 最后修改日期:2014-01-08
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  • 在线发布日期: 2014-01-20
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