方法：选取IMH患者83例83眼作为研究对象，按照是否剥离内界膜及剥离内界膜方式分为两组，采用亮蓝(BBG)染色内界膜剥除术42例作为A组，采用无染色内界膜剥除术41例作为B组，并选取同期不剥除内界膜组40例作为对照组。

结果：术后随访6mo，A、B两组黄斑裂孔愈合例数(41例，40例)明显多于对照组(25例)，差异具有统计学意义(P<0.05)； A、B两组视力恢复程度明显优于对照组(P<0.05)； 术后A、B组患者多焦视网膜电图一阶函数的1环和2环的P1波反应密度均明显高于对照组(P<0.05)； A组内界膜剥除手术时间为(234.7±9.2)s，B组(168.4±7.2)s，A组长于B组(P<0.05)。

结论：玻璃体切割术中应用无染色视网膜内界膜剥除术视功能恢复程度更好，手术用时更少，同时避免了染色剂所致的视网膜毒性，适宜临床广泛推广和应用。

METHODS: Totally 83 patients(83 eyes)with idiopathic macular hole in our hospital were selected and randomly divided into two groups according to the inner limiting membrane peeling approach. The 42 cases of A group underwent inner limiting membrane peeling stained with brilliant blue G(BBG), while the other 41 cases of B group received inner limiting membrane peeling without staining. And at the corresponding period, 40 patients without inner limiting membrane peeling was selected as the control group.

RESULTS: Patients were followed up for 6mo, the amount of cases with healed macular hole in the A and B group(41, 40 patients respectively)was larger than that of the control group(25 patients)(P<0.05); the visual acuity recovery in A and B group was significantly better than the control group(P<0.05); evaluated by multifocal ERG, the P1 response densities of ring 1 and 2 of first-order function were significantly higher(P<0.05)than the control group; operation time spent in inner limiting membrane peeling was longer for group A(234.7±9.2s)than group B(168.4±7.2s)(P<0.05).

CONCLUSION: Application ofvitrectomy without inner limiting membrane staining can achieve better visual functional recovery with less surgical time. Meanwhile, it avoids the retinal toxicity caused by coloring agent. It is worthy of wider promotion and application.