AIM: To evaluate tear film recoveries and effects of sodium hyaluronate eye drops, deproteinized calf blood extract eye gel on tear film after vitrectomy.

METHODS: In 120 cases after vitrectomy, the patients were randomly divided into four groups, 30 cases for each group, group A were given the conventional medicine, group B in addition to conventional medicine, with sodium hyaluronate eye drops, group C in addition to conventional medicine, with deproteinized calf blood extract eye gel, group D in addition to conventional medicine with sodium hyaluronate eye drops and deproteinized calf blood extract eye gel. Tear break-up time(BUT), Schirmer I test(SⅠt)corneal fluorescein staining were measrued at 1d preoperatively plus 1, 3, 7, 14, 30d postoperatively. The results were analyzed statistically.

RESULTS:(1)Statistical significance was found in BUT, Sit at 1d preoperatively and 1, 3, 7, 14d postoperatively(P<0.01); BUT, ST recoveried original level 30d postoperatively.(2)All the four methods could recover fear film, but the result of group D was significantly better than other three groups.

CONCLUSION:Sodium hyaluronate eye drops combined with deproteinized calf blood extract eye gel as early as possible can accelerate the recovery of tear film after vitrectomy.