AIM: To explore the clinical efficacy and safety of self Yiqi Yangyin Sanyu Fang in treatment of dry eyes syndrome.

METHODS: Totally 78 patients(96 eyes)were randomly divided into two groups from January 2009 to December 2012 in Ophthalmology Department of our hospital, control group was given local artificial tears, the observation group was given artificial tears and Chinese medicine Yiqi Yangyin Sanyu Fang, Schirmer Ⅰ test(SⅠt), tear break-up time(BUT), corneal fluorescein staining(FL)and clinical efficacy of the two groups were compared.

RESULTS: After treatment, SⅠt, BUT of two groups were higher than that of before treatment, FL was lower than that of before treatment, the difference was statistically significant(P<0.05), after treatment SⅠt, BUT of observed group were higher than that of the control group, FL was lower than the control group, the difference was statistically significant(P<0.05); the efficiency rate of observation group was 83%, control group 71%, there were statistically significant differences in the two groups(Ridit z=24.382, P=0.000), the observation group effect was better than that of control group.

CONCLUSION: Chinese medicine Yiqi Yangyin Sanyu Fang have no obvious side effect, it can improve the clinical symptoms of dry eye syndrome and is worthy clinical application.